> ## Documentation Index
> Fetch the complete documentation index at: https://docs.biohub.ai/llms.txt
> Use this file to discover all available pages before exploring further.

# Get cluster info and member hashes for a representative protein

> Look up cluster metadata and member protein hashes for a cluster representative protein identified by its MD5 hash.



## OpenAPI

````yaml openapi/metagenomic-atlas-openapi.json GET /esm/protein/api/v1alpha1/clusters/{protein_hash}
openapi: 3.1.0
info:
  title: ESM Atlas API Reference
  description: Interfaces may change without notice.
  version: 0.1.0
servers:
  - url: https://biohub.ai
security: []
paths:
  /esm/protein/api/v1alpha1/clusters/{protein_hash}:
    get:
      tags:
        - Clusters
      summary: Get cluster info and member hashes for a representative protein
      description: >-
        Look up cluster metadata and member protein hashes for a cluster
        representative protein identified by its MD5 hash.
      operationId: get_cluster_detail_esm_protein_api_v1alpha1_clusters__protein_hash__get
      parameters:
        - name: protein_hash
          in: path
          required: true
          schema:
            type: string
            pattern: ^[0-9a-f]{32}$
            title: Protein Hash
        - name: topk_features
          in: query
          required: false
          schema:
            type: integer
            maximum: 100
            minimum: 1
            default: 10
            title: Topk Features
      responses:
        '200':
          description: Successful Response
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/ClusterDetailResponse'
        '422':
          description: Validation Error
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/HTTPValidationError'
components:
  schemas:
    ClusterDetailResponse:
      properties:
        protein_hash:
          type: string
          title: Protein Hash
        protein_name:
          anyOf:
            - type: string
            - type: 'null'
          title: Protein Name
        source:
          anyOf:
            - type: string
            - type: 'null'
          title: Source
        accession:
          anyOf:
            - type: string
            - type: 'null'
          title: Accession
        cluster_size:
          type: integer
          title: Cluster Size
        cluster_pct_characterized:
          type: integer
          title: Cluster Pct Characterized
        cluster_mean_domain_coverage:
          type: number
          title: Cluster Mean Domain Coverage
        member_protein_hashes:
          items:
            type: string
          type: array
          title: Member Protein Hashes
        cluster_top_pfam_domains:
          anyOf:
            - additionalProperties:
                $ref: '#/components/schemas/PfamDomainInfo'
              type: object
            - type: 'null'
          title: Cluster Top Pfam Domains
        cluster_representative_features:
          items:
            $ref: '#/components/schemas/SAEFeatureResponse'
          type: array
          title: Cluster Representative Features
          default: []
        cluster_taxonomy_info:
          anyOf:
            - $ref: '#/components/schemas/ClusterTaxonomyInfo'
            - type: 'null'
        top_phyla:
          anyOf:
            - additionalProperties:
                type: integer
              type: object
            - type: 'null'
          title: Top Phyla
        mean_plddt:
          anyOf:
            - type: number
            - type: 'null'
          title: Mean Plddt
        ptm:
          anyOf:
            - type: number
            - type: 'null'
          title: Ptm
      type: object
      required:
        - protein_hash
        - cluster_size
        - cluster_pct_characterized
        - cluster_mean_domain_coverage
        - member_protein_hashes
      title: ClusterDetailResponse
      description: >-
        Cluster details: metadata, member protein hashes, and representative SAE
        features.
    HTTPValidationError:
      properties:
        detail:
          items:
            $ref: '#/components/schemas/ValidationError'
          type: array
          title: Detail
      type: object
      title: HTTPValidationError
    PfamDomainInfo:
      properties:
        count:
          type: integer
          title: Count
        name:
          type: string
          title: Name
      type: object
      required:
        - count
        - name
      title: PfamDomainInfo
      description: Pfam domain occurrence count and human-readable name.
    SAEFeatureResponse:
      properties:
        feature_index:
          type: integer
          title: Feature Index
        label:
          type: string
          title: Label
        description:
          type: string
          title: Description
        value:
          type: number
          title: Value
        residue_regions:
          items:
            $ref: '#/components/schemas/ResidueRegion'
          type: array
          title: Residue Regions
          default: []
      type: object
      required:
        - feature_index
        - label
        - description
        - value
      title: SAEFeatureResponse
      description: An SAE feature that is activated for a protein.
    ClusterTaxonomyInfo:
      properties:
        rank:
          type: string
          title: Rank
        name:
          type: string
          title: Name
      type: object
      required:
        - rank
        - name
      title: ClusterTaxonomyInfo
      description: LCA (lowest common ancestor) taxonomy for a cluster.
    ValidationError:
      properties:
        loc:
          items:
            anyOf:
              - type: string
              - type: integer
          type: array
          title: Location
        msg:
          type: string
          title: Message
        type:
          type: string
          title: Error Type
        input:
          title: Input
        ctx:
          type: object
          title: Context
      type: object
      required:
        - loc
        - msg
        - type
      title: ValidationError
    ResidueRegion:
      properties:
        start:
          type: integer
          title: Start
        end:
          type: integer
          title: End
        peak_residue:
          type: integer
          title: Peak Residue
        mean_activation:
          type: number
          title: Mean Activation
      type: object
      required:
        - start
        - end
        - peak_residue
        - mean_activation
      title: ResidueRegion
      description: A contiguous stretch of residues where an SAE feature is active.

````