> ## Documentation Index
> Fetch the complete documentation index at: https://docs.biohub.ai/llms.txt
> Use this file to discover all available pages before exploring further.

# ESM3

> Represent, generate, and guide the design of novel proteins with ESM3.

<Card title="View tutorials on GitHub" icon="github" href="https://github.com/Biohub/esm/tree/main/cookbook/tutorials" horizontal />

<Columns cols={2}>
  <Card title="Understanding the ESMProtein class" icon="https://mintlify.s3.us-west-1.amazonaws.com/biohub-8940d923/icons/colab.svg" href="https://colab.research.google.com/github/Biohub/esm/blob/main/cookbook/tutorials/esmprotein.ipynb">
    Get familiar with how ESM3 represents proteins.
  </Card>

  <Card title="Generating proteins with ESM3" icon="https://mintlify.s3.us-west-1.amazonaws.com/biohub-8940d923/icons/colab.svg" href="https://colab.research.google.com/github/Biohub/esm/blob/main/cookbook/tutorials/esm3_generate.ipynb">
    Learn how to scaffold a functional motif, edit secondary structure, and guide design using
    solvent exposure.
  </Card>

  <Card title="Designing a novel GFP with ESM3" icon="https://mintlify.s3.us-west-1.amazonaws.com/biohub-8940d923/icons/colab.svg" href="https://colab.research.google.com/github/Biohub/esm/blob/main/cookbook/tutorials/gfp_design.ipynb">
    Walk through the exact prompting strategy used to design a novel fluorescent protein with no
    close natural relatives.
  </Card>

  <Card title="Guided generation with ESM3" icon="https://mintlify.s3.us-west-1.amazonaws.com/biohub-8940d923/icons/colab.svg" href="https://colab.research.google.com/github/Biohub/esm/blob/main/cookbook/tutorials/esm3_guided_generation.ipynb">
    Add scoring functions into the generation process, such as structural quality, sequence
    constraints, or other properties.
  </Card>
</Columns>