View tutorials on GitHub
Embedding sequences with ESMC
Embed protein sequences and explore how different transformer layers encode structural and
functional information.
Zero-shot entropy and mutation analysis
Compute per-position entropy and log-likelihood ratios to identify constrained vs.
mutation-tolerant sites.
Layer sweep for enzyme function classification
Learn how to sweep all layers to find which one is best using enzyme classification as a task.
Understanding proteins with SAE features
Extract and visualize sparse autoencoder features, rank by peak activation, and map activations
onto 3D structures.
Fine-tuning ESMC
Fine-tune a classification or regression head for your dataset on top of ESMC using Parameter
Efficient Fine-tuning (PEFT).